Anatomia patologica del carcinoma del polmone - immagini

Lung, adenocarcinoma

Note the gland-like structures lined by epithelial cells showing some nuclear atypia, e.g., angulation and variation in size.

Lung,small cell carcinoma

The top 1/3 of this specimen contains the small cell undifferentiated carcinoma seen as small tightly packed cells. There is early invasion. The cells may closely resemble lymphocytes in appearance or be spindle or polygonal in shape. This tumor is often centrally (hilar) located and shows a high correlation with cigarette smoking.

Lung, large cell undifferentiated carcinoma

Large cell carcinoma of the lung is a form of bronchogenic carcinoma arising from the bronchial epithelium. Histologically this cancer appears as aggregations of undifferentiated cells, as seen in this section. These cells are large compared with the cells seen in small cell carcinoma.

Bronchial washing, large cell undifferentiated carcinoma

The cell in the center of the screen shows malignant criteria in the form of: a high N/C; hyperchromasia; clearing and clumping of chromatin; angular chromatin and nucleolus; irregular thickness of and angulation of the nuclear border.

Lung,squamous cell carcinoma

This tumor has cells which are poorly differentiated. Note the many layers of flattened, eosinophilic cells that occupy 80% or more of this specimen. The marked eosinophilia of the cells is due to the presence of large amounts of cytoplasmic keratin . This is a characteristic specimen of squamous cell carcinoma. This type of cancer typically arises in the central (hilar) portion of the lung and has the closest correlation with smoking of any of the bronchogenic cancers.

Lung, bronchioloalveolar cell carcinoma (airway cast)

This gross specimen is a cast of a portion of the airway of the lung. Bronchioalveolar carcinoma does not form a discrete mass. Rather this cancer travels along the airway replacing the respiratory epithelium with a tall, columnar, mucin producing cell type that forms papillary projections into the lumen of the airway.