I

Malattia confinata nella capsula della pleura parietale: pleura ipsilaterale, polmone, pericardio e diaframma.

T1 N0 MO

T2 N0 M0

II

All of stage I with positive intrathoracic (N1 or N2) lymph nodes.

T1 N1 M0

T2 N1 M0

III

Local extension of disease into the following: chest wall or mediastinum: heart or through the diaphragm, periotoneum; with or without extrathoracic or contralateral (N3) lymph node involvement.

T3 NO MO

T3 N1 M0

T1 N2 M0

T2 N2 M0

T3 N2 M0

IV

Distant metastatic disease

Any T N3 MO

T4 any N M0

Any T and N M1

T

(Primary Tumour and Extent)

TX

Primary tumour cannot be assessed

T0

No evidence of primary tumour

T1

Primary tumour limited to ipsilateral parietal or visceral pleura

T2

Tumour invades any of the following: ipsilateral lung, endothoracic fascia, diaphragm, pericardium

T3

Tumour invades any of the following: ipsilateral chest wall muscle, ribs, mediastinal organs or tissues

T4

Tumour extends to any of the following: contralateral pleura or lung by direct extension, peritoneum or intra-abdominal organs by direct extension, cervical tissues

N

NX

Regional lymph nodes cannot be assessed

NO

No regional lymph nodes metastases

N1

Metastases in ipsilateral bronchopulmonary of hilar lymph nodes

N2

Metastases in ipsilateral mediastinal lymph nodes

N3

Metastases in contralateral mediastinal internal mammary, supraclavicular, or scalene lymph nodes

M

(Metastases)

MX

Presence of distant metastases cannot be assessed

M0

No known distant metastases

M1

Distant metastasis present